Fc-Fc interactions and immune inhibitory effects of IgG4: implications for anti-PD-1 immunotherapies.
Weifeng ZhangXueling ChenXingxing ChenJirui LiHui WangXiaomiao YanHan ZhaXiaonan MaChanyuan ZhaoMeng SuLiangli HongPenghao LiYanyu LingWenhui ZhaoYu XiaBaiyong LiTianjing ZhengJiang GuPublished in: Journal for immunotherapy of cancer (2024)
K and Fc-null IgG1 displayed similar structural properties and benefits. This study contributes to the understanding of immunotherapy resistance and the advancement of safer immune therapies for cancer.