Thrombotic microangiopathy associated with anticancer and immune system targeting drugs: New insights from real-world data using the WHO pharmacovigilance database.

Bérenger LargeauBenjamin ThoreauSteven GrangéAnnie-Pierre Jonville-BéraJean-Michel Halimi

Published in: Journal of internal medicine (2023)

Several recently marketed immune system targeting/anticancer drugs have been identified as potential new drugs associated with TMA, which will require confirmatory studies. The number of drugs associated with TMA reporting markedly increased within the past 10 years, primarily due to innovative anticancer drugs.

Keyphrases

adverse drug
drug induced
emergency department
electronic health record
big data
climate change
drug delivery
artificial intelligence
human health
case control