Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer.

Jixuan GaoMoonSun JungRebekka T WilliamsDanica HuiAmanda J RussellAndrea J NaimAlvin KamiliMolly CliftonAngelika BongersChelsea MayohGwo HoClare L ScottWendy JessupMichelle HaberMurray D NorrisMichelle J Hendersonnull On Behalf Of Australian Ovarian Cancer Study

Published in: Cancers (2022)

Our data demonstrate the importance of ABCA1 in maintaining cholesterol balance and malignant properties in EOC cells, highlighting its potential as a therapeutic target for this disease.

Keyphrases

low density lipoprotein
induced apoptosis
cell cycle arrest
signaling pathway
oxidative stress
machine learning
pi k akt
data analysis
artificial intelligence
deep learning