Association of ISL1 polymorphisms and eosinophilic levels among otitis media patients.

Abhishek KondyarpuChinmay Sundar RayKhirod Chandra PandaNarayan Chandra BiswalPuppala Venkat Ramchander

Published in: Journal of clinical laboratory analysis (2021)

Ours is the first report which shows a significant association of ISL1 variants (rs2303751 and rs121913540) with hearing-related disorder like otitis media in humans. These results implicate the possible role of ISL1 gene in the etiopathology of otitis media. The replication of the study in other ethnic populations may strengthen our findings.

Keyphrases

end stage renal disease
copy number
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
genome wide
gene expression
transcription factor
hearing loss