A lack of a definite correlation between male sub-fertility and single nucleotide polymorphisms in sperm mitochondrial genes MT-CO3, MT-ATP6 and MT-ATP8.

Mazhar Salim Al ZoubiMohamad Eid HammadehFatina W DahadhahMohammad A Al SmadiMazhar Salim Al ZoubiManal Issam Abu AlarjahHouda Amor

Published in: Molecular biology reports (2022)

The results of our study suggest that male sub-fertility is linked with rs7520428 SNP in MT-CO3 and MT-ATP6. The studied polymorphic variations in the MT-ATP8 gene, on the contrary, did not reveal any significant association with male sub-fertility.

Keyphrases

genome wide
oxidative stress
young adults
transcription factor
high density