Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization.
Ken KumagaiTakahiro ShimizuAtsushi TakaiNobuyuki KakiuchiYasuhide TakeuchiTomonori HiranoHaruhiko TakedaAya MizuguchiMari TeramuraTakahiko ItoEriko IguchiMitsuhiro NikaidoYuji EsoKen TakahashiYoshihide UedaShin'ichi MiyamotoKazutaka ObamaSeishi OgawaHiroyuki MarusawaHiroshi SenoPublished in: Cancer research (2022)
This study contributes to our understanding of gastric intestinal metaplasia as a risk factor for gastric adenocarcinoma via their multifocal expansion and acquisition of CNAs and somatic mutations.