Leg ulcers in sickle cell disease patients.
Paula Dadalti GranjaSamuel Braulio Magalhães QuintãoFranciele PerondiRosemary Bacellar Ferreira de LimaCláudia Labriola de Medeiros MartinsMarcos Arêas MarquesJúlio César Peclat de OliveiraPublished in: Jornal vascular brasileiro (2020)
Leg ulcers are the most common cutaneous complication of sickle cell disease. These lesions occur mainly in homozygous forms, are slow to heal and often relapse, causing negative physical, emotional, and economic impacts. In this paper, we discuss the clinical presentation, diagnosis, and pathophysiology of sickle cell leg ulcers and their implications for treatment.