Protective Actions of Cannabidiol on Aging-Related Inflammation, Oxidative Stress and Apoptosis Alterations in Liver and Lung of Long Evans Rats.

Lisa Rancan Beatriz Linillos-PradilloJulia CentenoSergio D ParedesElena VaraJesús A F Tresguerres

Published in: Antioxidants (Basel, Switzerland) (2023)

Chronic treatment with CBD in 15-month-old rats showed beneficial effects in lung and more significantly in liver by reducing the levels of inflammatory, oxidative and apoptotic mediators, and hence the cell damage associated with these three processes inherent to aging.

Keyphrases

oxidative stress
diabetic rats
ischemia reperfusion injury
dna damage
induced apoptosis
cell death
single cell
cell therapy
heat shock
drug induced
cell cycle arrest
combination therapy
mesenchymal stem cells