What is a clinically meaningful change in exhaled nitric oxide for children with asthma?
Shona FieldingMarielle PijnenburgJohan de JongsteKatharine C PikeGraham RobertsHelen PetskyAnne B ChangMaria FritschThomas FrischerStanley J SzeflerPeter GergenFrançoise VermeulenRobin VaelStephen W TurnerPublished in: Pediatric pulmonology (2020)
Over a 3-month period where FE NO is initially <50 ppb, a rise of <10 ppb or of <50% (based on IQR) is unlikely to be related to asthma. When FE NO is initially ≥50 ppb an percentage change of <50% (based on IQR) is unlikely to be asthma-related.