Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Jie WangMeng-Bin QinQing WuHuiying YangBiwei WeiJinlian XieYingying QinZhihai LiangJie'an HuangPublished in: BioMed research international (2022)
Hypertriglyceridemia downregulates the TJ proteins in PDECs, which may impair the pancreatic ductal mucosal barrier function. LSR regulation can change the effects of HTG on cellular barrier function by upregulating the TJ proteins.