The MOG antibody non-P42 epitope is predictive of a relapsing course in MOG antibody-associated disease.

Ganesha LiyanageBenjamin P TrewinJoseph A LopezJane AndersenFiona TeaVera MerhebKristy NguyenFiona X Z LeeMarzena J Fabis-PedriniAlicia ZouAli BucklandAnthony FokMichael Harry Barnett Stephanie BarnesRomain MarignierAseel El HajjMastura MonifAnneke Van Der WaltJeannette Lechner-ScottAllan G Kermode Tomas Kalincik Simon A Broadley Russell C Dale Sudarshini Ramanathan Fabienne Brilotnull null

Published in: Journal of neurology, neurosurgery, and psychiatry (2024)

Non-P42 MOG-IgG predicts a relapsing course in a significant subgroup of MOGAD patients. Patients with unilateral optic neuritis, the most frequent MOGAD phenotype, can reliably be tested at onset, regardless of age and sex. Early detection and specialised management in these patients could minimise disability and improve long-term outcomes.

Keyphrases

end stage renal disease
multiple sclerosis
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
rheumatoid arthritis
patient reported outcomes