Tumor immune microenvironment in therapy-naive esophageal adenocarcinoma could predict the nodal status.

Andromachi KotsaftiMatteo FassanFrancesco CavallinValentina AngerilliLuca SaadehMatteo CagolRita AlfieriPierluigi PilatiCarlo CastoroIgnazio CastagliuoloMelania Scarpa Melania Scarpa

Published in: Cancer medicine (2022)

Our data suggest that immune surveillance failure is the main driver of nodal metastasis onset. Moreover, nodal metastasis containment also involves the immune microenvironment of the peritumoral healthy tissue.

Keyphrases

lymph node
neoadjuvant chemotherapy
stem cells
squamous cell carcinoma
public health
electronic health record
hiv infected
big data
radiation therapy
mesenchymal stem cells
data analysis