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Serum-free light chain test utilisation at a South African academic laboratory and comparison with serum protein electrophoresis results.

Razia B BanderkerFatima B FazelAnnalise E ZemlinAye-Aye KhineThumeka P Jalavu
Published in: African journal of laboratory medicine (2023)
The study adds to the evidence on SFLC test utilisation. Serum protein electrophoresis alone may miss cases of light chain myeloma, while SFLC performed in isolation may produce false positive results in the setting of inflammatory disorders or renal impairment, leading to unnecessary further investigation.
Keyphrases
  • protein protein
  • oxidative stress
  • amino acid
  • multiple myeloma
  • small molecule
  • newly diagnosed