Serum-free light chain test utilisation at a South African academic laboratory and comparison with serum protein electrophoresis results.
Razia B BanderkerFatima B FazelAnnalise E ZemlinAye-Aye KhineThumeka P JalavuPublished in: African journal of laboratory medicine (2023)
The study adds to the evidence on SFLC test utilisation. Serum protein electrophoresis alone may miss cases of light chain myeloma, while SFLC performed in isolation may produce false positive results in the setting of inflammatory disorders or renal impairment, leading to unnecessary further investigation.