Short-term acipimox treatment is associated with decreased cardiac parasympathetic modulation.
Esben Thyssen VestergaardSimon Lebech CichoszNiels MøllerJens Otto Lunde JørgensenJesper FleischerPublished in: British journal of clinical pharmacology (2017)
Short-term inhibition of lipolysis by acipimox treatment lowered circulating FFA levels, improved insulin sensitivity, and was accompanied by reduced parasympathetic tone. The effect of acipimox on the parasympathetic modulation was reversed by hyperinsulinaemia.