Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics.
Antonio RampinoSilvia TorrettaBarbara GelaoFederica VenezianiMatteo IacovielloAleksandra MarakhovskayaRita MasellisIleana AndriolaLeonardo SportelliGiulio PergolaAlessandra MinelliChiara MagriMassimo GennarelliAntonio VitaJean Martin BeaulieuAlessandro BertolinoGiuseppe BlasiPublished in: European psychiatry : the journal of the Association of European Psychiatrists (2021)
Our findings suggest that, like GSK3β, FXR1 is affected by APs while shedding new light on the role of the FXR1/GSK3β pathway for NSs of SCZ.