Intraoperative methadone administration for total mastectomy: A single center retrospective study.

Juan P CataYusuf ZaidiJuan Jose Guerra-LondonoEvan D KharaschMatthew PiotrowskiSpencer KeeNicolas A Cortes-MejiaJose Miguel Gloria-EscobarPeter F ThallRuitao Lin

Published in: Journal of clinical anesthesia (2024)

Our study suggests that the unique pharmacological properties of methadone, including a short onset of action when given intravenously, long-acting pharmacokinetics, and multimodal effects, are associated with better acute pain management after a total mastectomy.

Keyphrases

pain management
chronic pain
liver failure
breast reconstruction
patients undergoing
intensive care unit
aortic dissection