HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer.

Andrej BesseLenka SedlarikovaLorina BuechlerMarianne KrausChieh-Hsiang YangNicol StrakovaKarel SoučekJiri NavratilMarek SvobodaAlana L WelmMarkus JoergerChristoph DriessenLenka Besse

Published in: British journal of cancer (2024)

Proteasome inhibition by carfilzomib combined with nelfinavir/lopinavir represents a potential treatment option for TNBC, warranting further investigation.

Keyphrases

multiple myeloma
antiretroviral therapy
hiv positive
hiv infected
human immunodeficiency virus
hiv aids
combination therapy
south africa