Non-oxidized and oxidized flaxseed orbitides differently induce HepG2 cell apoptosis: involvement of cellular uptake and membrane death receptor DR4.
Changmei PengJing LiAixiu ZhaoShaoqing YuLiufeng ZhengZe-Yuan DengPublished in: Journal of the science of food and agriculture (2024)
Non-oxidized flaxseed orbitides are more effective against cancer than oxidized flaxseed orbitides due to higher cellular uptake and activation of the DR4-mediated death receptor signaling pathway. © 2024 Society of Chemical Industry.