In Vivo Validation Model of a Novel Anti-Inflammatory Scaffold in Interleukin-10 Knockout Mouse.

Jung Yeon KimSo Young ChunSang Hoon LeeEugene LihJeongshik KimDae Hwan KimYun-Sok HaJae-Wook ChungJun Nyung LeeBum Soo KimHyun Tae KimEun Sang YooDong Keun HanTae Gyun KwonByung Ik Jang

Published in: Tissue engineering and regenerative medicine (2018)

These results indicate that the MH-PLGA scaffold had anti-inflammatory effects and high renal regeneration potency. Therefore, IL-10 KO mice are a suitable animal model for in vivo validation of novel anti-inflammatory scaffolds.

Keyphrases

anti inflammatory
tissue engineering
stem cells
drug delivery
high fat diet induced
type diabetes
metabolic syndrome
wound healing