Perinatal adversities in tuberous sclerosis complex: Determinants and neurodevelopmental outcomes.

Alexa X D ZhangHolan LiangFiona S McEwenCharlotte TyeEmma WoodhouseLisa UnderwoodElizabeth ShephardFintan Sheerinnull nullPatrick F Bolton

Published in: Developmental medicine and child neurology (2022)

Higher perinatal adversity is associated with familial tuberous sclerosis complex (TSC). Maternal TSC was associated with higher frequencies of several perinatal risk markers. Paternal TSC was not associated with higher levels of perinatal adversity. Perinatal adversity levels in TSC1 and TSC2 subgroups did not differ significantly. Perinatal adversities were not associated with neurodevelopmental outcomes.

Keyphrases

pregnant women
early life
early onset
skeletal muscle
pregnancy outcomes
birth weight
glycemic control
weight gain