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Increased circulating T follicular helper 13 subset correlates with high IgE levels in pediatric allergic asthma.

Xiao TongChaojiao GuanTuo JiCheng CaoJunfeng JiangMin LiuQin GuoPengcheng ZhouFang Gong
Published in: European journal of immunology (2022)
We found an elevation of circulating TFH13 cell subset in asthmatic children and the frequency of TFH13 cells positively correlated with the plasma dust mite-specific IgE levels. These results indicated that TFH13 cell subset may be responsible for the immunopathogenesis of excessive IgE accumulation in children with allergic asthma.
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