Distinct age-adjusted D-dimer threshold to rule out acute pulmonary embolism in outpatients and inpatients.

Using the immunoturbidimetric method to measure DD, an age-adjusted DD cutoff (age × 10 μg/L, if aged >50 years) should be considered for outpatients with suspected PE. For inpatients, increasing the DD cutoff value to at least 2 × ULN yields the best test performance.