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Metal-Free Direct C-H Cyanoalkylation of Quinoxalin-2(1 H)-Ones by Organic Photoredox Catalysis.

Wei ZhangYu-Liang PanChen YangLi ChenXin LiJin-Pei Cheng
Published in: The Journal of organic chemistry (2019)
Green and efficient C-C bond cleavage/cyanoalkylation of quinoxalin-2(1 H)-ones and other heteroarenes under visible light or sunlight irradiation is described. The reaction proceeds under mild conditions at room temperature without transition-metal catalysts and extra bases. Notably, the products enable facile transformations to various significant organic compounds.
Keyphrases
  • visible light
  • transition metal
  • room temperature
  • ionic liquid
  • water soluble
  • dna binding
  • radiation therapy
  • highly efficient