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Phosphazenomalonates as Catalysts and Reactants in (4+3) Annulation to Acrolein.

Konstantin L IvanovMikhail Ya MelnikovEkaterina M Budynina
Published in: Organic letters (2019)
The concept of combining a catalyst and an activated center in one molecule was implemented in Michael donors functionalized with phosphazene units. First, the phosphazene group catalyzes Michael addition and then acts as a reactant in an intramolecular aza-Wittig reaction. The viability of this strategy was demonstrated by our development of a one-pot method for azepane core construction starting from functionalized azides, triphenylphosphine and acrolein.
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