Pregnancy management and outcome after uterus transplantation.
I MendilciogluNasuh Utku DoganO OzkanM BahceciK BoynukalinS DoganO OzkanPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2022)
Uterus transplantation is a novel approach in women whose uterus is absent or severely abnormal. However, it is still an experimental procedure that poses risks to both the mother and baby. To date, 32 live births after uterus transplantation have been reported in peer-reviewed journals with several maternal, fetal, and neonatal complications. The most common complications were preterm delivery, hypertensive disorders and placenta previa. Four patients experienced episodes of transplant rejection during pregnancy. The appropriate management of complicated and non-complicated pregnancies is still controversial. In this review, obstetric outcomes after uterus transplantation and optimal management during pregnancy are discussed in light of the available data. This article is protected by copyright. All rights reserved.
Keyphrases
- pregnancy outcomes
- preterm birth
- end stage renal disease
- cell therapy
- pregnant women
- newly diagnosed
- blood pressure
- risk factors
- ejection fraction
- chronic kidney disease
- stem cells
- systematic review
- type diabetes
- polycystic ovary syndrome
- electronic health record
- climate change
- metabolic syndrome
- birth weight
- minimally invasive
- physical activity
- big data
- human health
- artificial intelligence
- patient reported outcomes
- weight gain
- meta analyses
- breast cancer risk