SARS-CoV-2 spike protein acts as a β-adrenergic receptor agonist: A potential mechanism for cardiac sequelae of long COVID.

Xiangning DengHongtu CuiHao LiangXinyu WangHaiyi YuJingjia WangWenyao WangDongyang LiuYouyi ZhangErdan DongYida TangHan Xiao

Published in: Journal of internal medicine (2024)

Severe acute respiratory syndrome-coronavirus-2 spike proteins act as an allosteric β-AR agonist, leading to cardiac β-AR hyperactivity, thus contributing to PASC-CVS.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
left ventricular
small molecule
heart failure
protein protein
risk assessment
binding protein