Efficacy and Safety of Tacrolimus or Infliximab Therapy in Children and Young Adults With Acute Severe Colitis.

Lori A ZimmermanJonathan SpaanNathan WeinbrenKrishanth ManokaranAravindh AjithkumarAnna BogurskyEnju LiuCraig LilleheiBrent R WeilJill M ZalieckasAthos BousvarosPaul A Rufo

Published in: Journal of pediatric gastroenterology and nutrition (2023)

There were no significant differences in the likelihood of colectomy 6 months after initiating IFX or TAC rescue therapy. Efficacy of both agents was comparable. The types of adverse effects differed by therapy. These data support the use of either TAC or IFX in children with ASC refractory to intravenous corticosteroids.

Keyphrases

young adults
high dose
liver failure
intensive care unit
drug induced
mesenchymal stem cells
low dose
cell therapy
artificial intelligence
acute respiratory distress syndrome
data analysis