Eremantholide C from aerial parts of Lychnophora trichocarpha, as drug candidate: fraction absorbed prediction in humans and BCS permeability class determination.
Tamires Guedes CaldeiraDênia Antunes Saúde-GuimarãesIsabel González-ÁlvarezMarival BermejoJacqueline de SouzaPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2021)
The high permeability, in addition to the low solubility, indicated that eremantholide C is a biologically active substance BCS class II. The pharmacological activities, low toxicity and biopharmaceutics parameters demonstrate that eremantholide C has the necessary requirements for the development of a drug product, to be administered orally, with action on inflammation, hyperuricemia and gout.