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S- and P-type cobra venom cardiotoxins differ in their action on isolated rat heart.

Alexey S AverinMikhail V GoltyaevTatyana V AndreevaVladislav G StarkovVictor I TsetlinYuri N Utkin
Published in: The journal of venomous animals and toxins including tropical diseases (2022)
The P-type cardiotoxin CTX-2 more strongly impairs rat heart functional activity than the S-type cardiotoxin CTX-1, as expressed in its faster blockage of cardiac contractions as well as in more rapid development and greater magnitude of contracture in its presence.
Keyphrases
  • heart failure
  • oxidative stress
  • klebsiella pneumoniae
  • atrial fibrillation
  • sensitive detection