Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies.

Timo O OdiniusLars BuschhornCelina WagnerRichard T HauchVeronika DillMarta DechantMichele C BuckKhalid ShoumariyehPhilipp MoogJuliana SchwaabAndreas ReiterKnut BrockowKatharina GötzeFlorian BassermannUlrike HöckendorfCaterina BrancaPhilipp J JostStefanie Jilg

Published in: Journal of cancer research and clinical oncology (2021)

Our study shows that MCL1 inhibition might be a promising therapeutic option for hypereosinophilia patients specifically for CEL-NOS and MLN-Eo.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
nitric oxide
patient reported outcomes
patient reported