Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens.

Madoka Sakata-MatsuzawaKaori Denda-NagaiHaruhiko FujihiraMiki NojiKatrin Beate Ishii-SchradeAtsushi MatsudaAtsushi KunoMisato OkazakiKatsuya NakaiYoshiya HorimotoMitsue SaitoTatsuro Irimura

Published in: PloS one (2021)

TNBC cells from relapsed patients showed a unique lectin reactivity, with higher levels of TJA-II (also WFA and BPL) binding than in non-relapsed patients. The results are potentially useful to develop new prognostic and therapeutic tools.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
acute lymphoblastic leukemia
peritoneal dialysis
multiple myeloma
high throughput
mass spectrometry
binding protein
ultrasound guided
dna binding