The Relevance of Biologically Effective Dose for Hearing Preservation After Stereotactic Radiosurgery for Vestibular Schwannomas: A Retrospective Longitudinal Study.
Constantin TuleascaIuliana Toma-DasuSebastien DurouxDaniele StarnoniMercy GeorgeRaphael MaireRoy Thomas DanielDavid PatinLuis SchiappacasseAlexandru DasuMohamed FaouziMarc LevivierPublished in: Neurosurgery (2023)
Our analysis showed that risk of hearing decline was associated with male sex, higher radiation dose rate (cutoff 2.5 Gy/minute), higher integral dose received by the tumor, higher beam-on time ≥20 minutes, and lower BED. A BED between 55 and 61 was considered as optimal for hearing preservation.