Leucomethylene blue probe detects a broad spectrum of reactive oxygen and nitrogen species.
Christopher CremerJean Michél MerkesChristina L BubDirk RommelFrederic W PatureauSrinivas BanalaPublished in: RSC advances (2021)
Reactive oxygen and nitrogen species (ROS, RNS) are ubiquitous in biology with a variety of physiological and pathological functions. Here we describe a broad spectrum ROS/RNS detecting fluorogenic probe with red fluorescence emission and up to 100-fold gain. Hence these modified probes are useful for in vivo non-invasive quantification of ROS/RNS.