Trajectory of spirometric and exhaled nitric oxide measurements in Chinese schoolchildren with asthma.
Ting-Fan LeungMan F TangAgnes S Y LeungWilson W S TamHing Y SyGary Wing Kin WongPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2017)
Asthmatic children have annual decline in FVC and increase in FEV1 /FVC and FEF25-75 . Their lung function trajectory is influenced by gender, ICS treatment, BMI, and asthma exacerbations. IL33 and GSDMB may be candidate genes for their lung function growth.