Bing-Neel Syndrome and Coexisting Pituitary Macroadenoma in a Patient with Waldenström Macroglobulinemia Revealed by 18 F-FDG and 68 Ga-Pentixafor PET/CT.
Qingqing PanYaping LuoXinxin CaoJian LiJun FengPublished in: Diagnostics (Basel, Switzerland) (2023)
A 63-year-old man presenting with peripheral neuropathies was diagnosed of Waldenström's macroglobulinemia, and Bing-Neel syndrome was subsequently confirmed via cerebrospinal fluid examinations. Besides involvement in bone marrow, lymph nodes, as well as the thoracic and sacral nerve root, 68 Ga-Pentixafor PET/CT detected active tracer uptake in bilateral choroid plexus, which was negative in 18 F-FDG PET/CT, possibly suggesting the involvement of Bing-Neel syndrome. The coexisting pituitary macroadenoma was FDG-avid but negative in 68 Ga-Pentixafor PET/CT. After six cycles of chemotherapy, the follow-up PET/CT showed complete remission of the previous disease, including the high uptake of 68 Ga-Pentixafor in choroid plexus. However, the hypermetabolic pituitary macroadenoma remained unchanged.
Keyphrases
- pet ct
- case report
- positron emission tomography
- bone marrow
- lymph node
- cerebrospinal fluid
- growth hormone
- spinal cord
- squamous cell carcinoma
- early stage
- pet imaging
- ulcerative colitis
- radiation therapy
- locally advanced
- rheumatoid arthritis
- computed tomography
- spinal cord injury
- disease activity
- rectal cancer
- systemic lupus erythematosus
- sentinel lymph node