FLI-06 Intercepts Notch Signaling And Suppresses The Proliferation And Self-renewal Of Tongue Cancer Cells.

Rui-Huan GanLi-Song Lin Jing XieLi HuangLin-Can DingBo-Hua SuXian-E PengDa-Li ZhengYou-Guang Lu

Published in: OncoTargets and therapy (2019)

FLI-06 can block the proliferation and self-renewal of tongue cancer cells. It is inferred that this compound, which inhibits the Notch signaling pathway, may serve as a potential targeted drug for the treatment of tongue cancer in the clinic.

Keyphrases

signaling pathway
pi k akt
induced apoptosis
epithelial mesenchymal transition
papillary thyroid
primary care
cell proliferation
squamous cell
cancer therapy
squamous cell carcinoma
emergency department
climate change
combination therapy
adverse drug
drug delivery