Potential drug-drug interactions associated with drugs currently proposed for COVID-19 treatment in patients receiving other treatments.

Florian LemaitreCaroline SolasMatthieu GregoireLaurence LagarceLaure ElensElisabeth PolardBéatrice Saint-SalviAgnès SommetMichel TodChantal Barin-Le Guellecnull null

Published in: Fundamental & clinical pharmacology (2020)

Patients with COVID-19 are sometimes already being treated for one or more other chronic conditions, especially if they are elderly. Introducing a treatment against COVID-19, either on an outpatient basis or during hospitalization for more severe cases, raises the question of potential drug-drug interactions. Here, we analyzed the potential or proven risk of the co-administration of drugs used for the most common chronic diseases and those currently offered as treatment or undergoing therapeutic trials for COVID-19. Practical recommendations are offered, where possible.

Keyphrases

coronavirus disease
sars cov
emergency department
human health
climate change
replacement therapy
adverse drug