Autoimmune gastritis induces aberrant DNA methylation reflecting its carcinogenic potential.

Chihiro TakeuchiJunichi SatoSatoshi YamashitaAkiko SasakiTakemi AkahaneRika AokiMitsue YamamichiYu-Yu LiuMasayoshi ItoTakahisa FurutaShigemi NakajimaYoshiki SakaguchiYu TakahashiYosuke TsujiKeiko NiimiShuta TomidaMitsuhiro FujishiroNobutake YamamichiToshikazu Ushijima

Published in: Journal of gastroenterology (2022)

AIG induced aberrant DNA methylation in gastric mucosa. However, the degree of DNA methylation was less than that by HPG, which reflected carcinogenic risk.

Keyphrases

dna methylation
genome wide
gene expression
helicobacter pylori
multiple sclerosis
drug induced
copy number
helicobacter pylori infection
polycyclic aromatic hydrocarbons
diabetic rats
oxidative stress
risk assessment