Sentinel lymph node biopsy without axillary lymphadenectomy after neoadjuvant chemotherapy is accurate and safe for selected patients: the GANEA 2 study.

Jean-Marc ClasseCecile LoaecP GimberguesS AlranC Tunon de LaraP F DupreRoman RouzierC FaureN PaillocherM P ChauvetG HouvenaeghelM GutowskiP De BlayJ L VerhaegheE BarrangerC LefebvreC NgoG FerronC PalpacuerL Campion

Published in: Breast cancer research and treatment (2018)

In patients with no initial node involvement, negative SLN after NAC allows to safely avoid an ALND. Residual breast tumor and lympho-vascular invasion after NAC allow identifying patients with initially involved node with a low risk of ALND involvement.

Keyphrases

sentinel lymph node
neoadjuvant chemotherapy
lymph node
early stage
locally advanced
transcription factor
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
high resolution
ultrasound guided
radiation therapy
lymph node metastasis