Immune checkpoint molecules soluble program death ligand 1 and galectin-9 are increased in pregnancy.
Elizabeth Ann L EnningaSusan M HarringtonDouglas J CreedonRodrigo RuanoSvetomir N MarkovicHaidong DongRoxana S DroncaPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
Immune-regulatory molecules galectin-9 and sPD-L1 increased during pregnancy and may play a role in immune tolerance that is critical for the fetus.