Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro.

Mei Tong He Ah Young Lee Chan Hum Park Eun Ju Cho

Published in: Nutrition research and practice (2019)

CM exhibited radical scavenging activity and protective effect against H2O2 as indicated by the increased cell viability, decreased ROS production, down-regulation of inflammation-related proteins as well as p-p38, p-JNK, and p-ERK protein levels. Therefore, we suggest that CM could play the protective role from oxidative stress in glial cells.

Keyphrases

hydrogen peroxide
induced apoptosis
oxidative stress
signaling pathway
dna damage
nitric oxide
cell death
endoplasmic reticulum stress
cell cycle arrest
diabetic rats
pi k akt
ischemia reperfusion injury
cell proliferation
reactive oxygen species
amino acid
heat shock