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GSDMD and GSDME synergy in the transition of acute kidney injury to chronic kidney disease.

Zhengyue ChenCaiming ChenKunmei LaiChengkun WuFan WuZhimin ChenKeng YeJingzhi XieHuabin MaHong ChenYujia WangYanfang Xu
Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)
GSDMD and GSDME collaborate to contribute to AKI and subsequent renal fibrosis induced by folic acid. Synchronous inhibition of GSDMD and GSDME could be an innovative therapeutic strategy for mitigating the AKI-CKD transition.
Keyphrases
  • acute kidney injury
  • chronic kidney disease
  • cardiac surgery
  • end stage renal disease