Rapid communication: insights into the role of extracellular vesicles during Auger radioimmunotherapy.
Jihad KaramJulie ConstanzoAlexandre PichardLaurent GrosJoël ChopineauMarie MorilleJean-Pierre PougetPublished in: International journal of radiation biology (2021)
This study demonstrates that sEVs could play a role during Auger RIT through bystander effects in vitro. No systemic effects were observed in vivo, under our experimental conditions. However, X-rays experiments showed that sEVs collection time might be influencing the nature of sEVs, a parameter that should also be investigated during Auger RIT.
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