P18: Novel Anticancer Peptide from Induced Tumor-Suppressing Cells Targeting Breast Cancer and Bone Metastasis.
Changpeng CuiQingji HuoXue XiongSungsoo NaMasaru MitsudaKazumasa MinamiBai-Yan LiHiroki YokotaPublished in: Cancers (2024)
This study introduced a unique methodology for selecting an effective ACP from the iTSC secretome. P18 holds promise for the treatment of breast cancer and the prevention of bone destruction by regulating GTPase signaling.
Keyphrases
- bone mineral density
- induced apoptosis
- signaling pathway
- soft tissue
- bone loss
- cell cycle arrest
- bone regeneration
- high glucose
- diabetic rats
- postmenopausal women
- oxidative stress
- drug induced
- cancer therapy
- endoplasmic reticulum stress
- replacement therapy
- young adults
- endothelial cells
- machine learning
- deep learning
- smoking cessation