Surgical treatment confers prognostic significance in pediatric malignant mediastinal germ cell tumors.

Ting-Huan Huang Giun-Yi HungTe-Fu WengFu-Mien WangChih-Ying LeeDong-Tsamn LinBow-Wen ChenKai-Hsin LinKang-Hsi WuHsi-Che LiuJiann-Shiuh ChenShiann-Tarng JouJen-Yin HouYung-Li YangShih-Hsiang ChenHsiu-Hao ChangShyh-Shin ChiouPei-Chin LinRong-Long ChenChih-Cheng HsiaoHsiu-Ju YenChao-Ping YangTe-Kau ChangMeng-Yao LuChao-Neng ChengJiunn-Ming SheenYu-Mei LiaoMin-Yu Su Ting-Chi Yehnull null

Published in: Cancer (2022)

Surgical treatment is recommended for mediastinal GCT. Cisplatin-based chemotherapy was not superior to carboplatin-based chemotherapy as first-line treatment and may be avoided due to toxicity concerns.

Keyphrases

germ cell
lymph node
locally advanced
ultrasound guided
phase ii study
oxidative stress
squamous cell carcinoma
chemotherapy induced
childhood cancer