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Immunotherapy-induced severe neutropenia with neurotoxicity: A case of a 75-year-old woman with ulcerative colitis diagnosed with melanoma.

Rima PatelLori Pai
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2019)
Though hematologic malignancies of immune checkpoint inhibitors are rare, they should be considered after other diagnoses are excluded. We discuss the serious immune-related adverse effects of immune checkpoint inhibitors in a patient with an underlying autoimmune disease and general treatment approaches.
Keyphrases
  • ulcerative colitis
  • drug induced
  • high glucose
  • multiple sclerosis
  • case report
  • diabetic rats
  • early onset
  • oxidative stress
  • endothelial cells
  • combination therapy
  • adverse drug
  • smoking cessation