Current real-life use of vasopressors and inotropes in cardiogenic shock - adrenaline use is associated with excess organ injury and mortality.

Tuukka TarvasmäkiJohan LassusMarjut VarpulaAlessandro SionisReijo SundLars KøberJindrich SpinarJohn ParissisMarek BanaszewskiJose Silva CardosoValentina CarubelliSalvatore Di SommaAlexandre MebazaaVeli-Pekka Harjolanull null

Published in: Critical care (London, England) (2016)

Among vasopressors and inotropes, adrenaline was independently associated with 90-day mortality in CS. Moreover, adrenaline use was associated with marked worsening in cardiac and renal biomarkers. The combined use of noradrenaline with either dobutamine or levosimendan appeared prognostically similar.

Keyphrases

cardiovascular events
risk factors
cardiac surgery
coronary artery disease
type diabetes
cardiovascular disease
acute kidney injury