Polyps and colorectal cancer in serrated polyposis syndrome: contribution of the classical adenoma-carcinoma and serrated neoplasia pathways.
David E F W M van ToledoJoep E G IJspeertHannah BoersmaAlex R MuslerArne G C BleijenbergEvelien DekkerCarel J M van NoeselPublished in: Clinical and translational gastroenterology (2023)
Our study indicates that in SPS patients the ratio of sCRCs:aCRCs on average is fifty:fifty. This elevated sCRC:aCRC ratio in SPS patients, as compared to non-SPS patients, correlates well with the differences in the ratios of the numbers of sessile serrated lesions and conventional adenomas in SPS and non-SPS patients respectively.