Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis.
Paul AlexanderDiane Heels-AnsdellReed SiemieniukNeera BhatnagarYaping ChangYutong FeiYu-Qing ZhangShelley McLeodKameshwar PrasadGordon GuyattPublished in: BMJ open (2016)
DHC in SO-MCAi results in large reductions in mortality. Most of those who would otherwise have died are left with severe or very severe disability: for example, inability to walk and a requirement for help with bodily needs, though uncertainty about the proportion with very severe, severe and moderate disability remains (low to moderate quality/confidence/certainty evidence).