Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels.

Naif Khalaf Al HarbiFahad AljamaanHaya A AljamiMohammed W AlenaziHind AlbalawiAbdulrahman AlmasoudFatima J AlharthiEsam Ibraheem AzharTlili BarhoumiMohammad BosaeedSarah C GilbertAnwar M Hashem

Published in: Vaccines (2022)

MVA-MERS vaccine, administered in a homologous prime-boost regimen, induced high levels of neutralising anti-MERS-CoV antibodies in mice and camels. This could be considered for further development and evaluation as a dromedary vaccine to reduce MERS-CoV transmission to humans.

Keyphrases

respiratory syndrome coronavirus
sars cov
coronavirus disease
high dose
high fat diet induced
low dose
dna damage
type diabetes
dna repair
metabolic syndrome
skeletal muscle